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Hormones

Cabergoline
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Conjugated Estrogens
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Cyproterone acetate and ethinylestradiol
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Cytomel
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Diane 35
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Dostinex
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Dydrogesterone
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Eltroxin
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Eutroxsig
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Levothyroxine
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Liothyronine
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Medrol
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Medrol Active
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Mestinon
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Methimazole
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Understanding Hormones and Hormone Therapy

Hormones are chemical messengers produced by various glands throughout your body, including the thyroid, adrenals, ovaries, and testes. These powerful substances regulate numerous bodily functions such as metabolism, growth, reproduction, mood, and sleep patterns. When hormone levels become imbalanced, it can significantly impact your overall health and quality of life.

Common hormone imbalances affect millions of Australians and can manifest through various symptoms including fatigue, weight changes, mood swings, sleep disturbances, hot flushes, irregular periods, and decreased libido. These imbalances may occur naturally due to ageing, menopause, or andropause, or result from medical conditions, stress, or lifestyle factors.

Hormone replacement therapy (HRT) offers several treatment options to restore hormonal balance. Available therapies include oestrogen and progesterone replacement for menopause, testosterone therapy for low testosterone levels, thyroid hormone replacement, and insulin therapy for diabetes management. These treatments come in various forms such as tablets, patches, gels, injections, and implants.

The benefits of hormone therapy can include improved energy levels, better mood stability, enhanced sleep quality, and reduced menopausal symptoms. However, considerations include potential side effects, individual health risks, and the need for regular monitoring. It's essential to consult with your GP or an endocrinologist to determine if hormone therapy is appropriate for your specific situation and to develop a personalised treatment plan.

Thyroid Hormones

Thyroid hormones play a crucial role in regulating your body's metabolism, energy production, heart rate, and body temperature. The thyroid gland produces primarily thyroxine (T4) and triiodothyronine (T3), which influence virtually every cell in your body. When thyroid function becomes disrupted, it can significantly affect your overall health and wellbeing.

The two most common thyroid conditions affecting Australians are hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid). Hypothyroidism symptoms include fatigue, weight gain, cold intolerance, and depression, whilst hyperthyroidism presents with weight loss, rapid heartbeat, anxiety, and heat intolerance.

Available Thyroid Medications in Australia

  • Levothyroxine: Available as Oroxine and Eutroxsig, these are the most commonly prescribed thyroid replacement medications
  • Liothyronine preparations: Provide T3 hormone for specific therapeutic needs
  • Combination thyroid products: Contain both T4 and T3 hormones for comprehensive treatment

Proper monitoring through regular blood tests is essential to ensure optimal dosing and therapeutic outcomes. Your healthcare provider will adjust dosages based on thyroid function tests and symptom assessment. Lifestyle factors such as diet, exercise, stress management, and timing of medication intake can significantly influence thyroid function and treatment effectiveness.

Oestrogen and Progesterone Therapy

Menopause brings significant hormonal changes as women's bodies naturally reduce oestrogen and progesterone production. These fluctuations can cause uncomfortable symptoms including hot flushes, night sweats, mood changes, and bone density loss. Hormone replacement therapy (HRT) offers effective relief by supplementing these declining hormones.

Benefits and Available Products

Oestrogen replacement therapy can significantly improve quality of life by reducing menopausal symptoms and supporting bone health. Australian pharmacies stock various oestrogen formulations to suit individual needs:

  • Oral tablets: Premarin and Progynova offer convenient daily dosing
  • Patches and gels: Estradot patches and Sandrena gel provide steady hormone delivery
  • Vaginal preparations: Target localised symptoms like dryness and discomfort

Progesterone and Safety Considerations

Progesterone products, including combined oestrogen-progesterone preparations, protect the uterine lining in women who haven't had a hysterectomy. Treatment requires careful monitoring due to potential risks including blood clots and breast cancer. Contraindications include active liver disease, unexplained bleeding, and certain cardiovascular conditions.

Bioidentical hormones, molecularly identical to those produced naturally, are increasingly popular alternatives to synthetic versions. Your pharmacist can discuss the most suitable option based on your individual health profile and preferences.

Testosterone Replacement Therapy

Male hormone deficiency, often called andropause or hypogonadism, affects increasing numbers of Australian men. Low testosterone levels can develop gradually with age or result from medical conditions, significantly impacting physical and mental wellbeing.

Recognising Low Testosterone

Common symptoms include reduced energy, decreased muscle mass, low libido, mood changes, and difficulty concentrating. Blood tests can confirm testosterone deficiency and guide appropriate treatment decisions.

Treatment Options Available in Australia

Several effective testosterone replacement products are available through Australian pharmacies:

  • Topical gels: AndroGel and Testogel offer daily application with consistent absorption
  • Injections: Reandron provides long-acting relief, whilst Primoteston offers shorter-term options
  • Patches and implants: Alternative delivery methods for specific patient needs

Monitoring and Safety

Regular monitoring ensures treatment effectiveness and safety, including prostate health checks and cardiovascular assessments. Side effects may include skin irritation, mood changes, or sleep disturbances. Treatment approaches vary between younger men with medical conditions and older men experiencing age-related decline, requiring individualised therapy plans.

Growth Hormones and Specialised Treatments

Growth Hormone Deficiency Treatment

Growth hormone deficiency affects both children and adults, requiring careful diagnosis and treatment. In children, it can result in slower growth rates and shorter stature, whilst adults may experience decreased muscle mass, increased body fat, and reduced bone density. Several growth hormone products are available in Australia through specialist prescription, including recombinant human growth hormone formulations that are bioidentical to naturally produced hormones.

Other Specialised Hormone Treatments

Beyond growth hormones, pharmacies stock various specialised hormone treatments including insulin for diabetes management, cortisol replacement therapy for adrenal insufficiency, and fertility hormones for reproductive health. These medications require specialist consultation and ongoing monitoring to ensure safe and effective treatment outcomes.

All growth hormone and specialised hormone treatments require prescription from qualified specialists. Proper storage in refrigerated conditions and careful administration following healthcare provider instructions are essential for maintaining medication efficacy and patient safety.

Safety, Interactions, and Professional Guidance

Medical Supervision and Monitoring

Hormone therapy requires comprehensive medical supervision due to the complex nature of hormonal interactions within the body. Your healthcare provider will establish baseline measurements through blood tests and physical examinations before commencing treatment. Regular monitoring appointments are essential to assess treatment effectiveness, adjust dosages, and identify any potential adverse effects early.

Drug Interactions and Precautions

Hormone medications can interact with numerous other drugs, affecting their efficacy or increasing side effect risks. Common interactions include:

  • Blood thinning medications with oestrogen-containing therapies
  • Diabetes medications requiring adjustment with hormone treatments
  • Certain antibiotics and antifungal medications
  • Herbal supplements that may affect hormone levels

Professional Healthcare Support

Working closely with your GP and specialist endocrinologists ensures optimal treatment outcomes. Many hormone therapies are subsidised through the Pharmaceutical Benefits Scheme (PBS), making treatments more affordable for eligible patients. Your healthcare team will guide you through safely starting, adjusting, or discontinuing hormone therapy based on your individual health needs and treatment response. Never modify hormone therapy without professional consultation, as sudden changes can cause significant health complications.

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