Basic Assurans Information

• INN (International Nonproprietary Name): Sildenafil Citrate
• Brand names available in Australia: Assurans
• ATC Code: G04BE03 (for erectile dysfunction), C02KX05 (for pulmonary arterial hypertension)
• Forms & dosages: 20 mg tablets, 20 mg injections
• Manufacturers in Australia: Cipla Ltd
• Registration status in Australia: Prescription only
• OTC / Rx classification: Rx only

National Pharmacy Chains

Assurans is widely available in Australia, primarily through national pharmacy chains. Chemist Warehouse, Priceline, and TerryWhite are some of the most trusted names for getting Assurans. These outlets often provide price-sensitive options, making it easier for consumers to find affordable alternatives for their medication needs. Chemist Warehouse, in particular, is known for its competitive pricing and extensive stock on popular medications, including Assurans. Priceline offers promotions that can benefit those seeking discounted prices, while TerryWhite is often praised for its customer service and pharmacy consultations. This makes them standout options for purchasing Assurans, ensuring availability to all who need it.

Online Pharmacy Trends In Australia

The rise of e-pharmacies is reshaping how Australians access medications like Assurans. They offer convenience, allowing patients to order their prescriptions from the comfort of their homes. Regulatory considerations do exist for e-pharmacies to adhere to safety and quality standards. Telehealth has played a significant role in this shift, as e-prescriptions are becoming more commonplace, enabling easier access to Assurans through approved channels. This is particularly beneficial for those in remote areas or for patients who may need ongoing consultations. By linking healthcare providers with e-pharmacy platforms, patients gain more flexibility and timely access to their prescribed medications.

Price Ranges By Package Size

When examining the cost of Assurans, it’s essential to differentiate between purchases made through the Pharmaceutical Benefits Scheme (PBS) and those made at private pharmacies. Assurans 20 mg tablets typically range from approximately $10 to $30 depending on the source. PBS pricing can significantly lower costs, particularly for eligible patients, making medications like Assurans more accessible. In contrast, private pharmacies offer a broader range of pricing, often reflecting differences in packaging—such as blister packs of 10, 15, or 30 tablets. Due to these variations, consumers are encouraged to check with local pharmacists for the best price options. While Assurans is primarily a prescription medication, there are instances where it may be available without a prescription, making it even more accessible.

How It Works in the Body

Layman’s explanation

Understanding how sildenafil, commonly known as Assurans, works is simpler than it seems. This medication helps treat pulmonary arterial hypertension (PAH) by enhancing blood flow to the lungs. In PAH, the blood vessels in the lungs become narrowed, causing high blood pressure in these vessels.

When Assurans is taken, it helps relax the blood vessels, making it easier for blood to flow through. Picture it like using a garden hose: when the hose is pinched, water flow is restricted. Sildenafil removes that pinch, allowing blood to navigate through more freely, which alleviates strain on the heart and reduces symptoms.

Clinical detail

Diving into the science, sildenafil’s pharmacodynamics involves the inhibition of phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP). By preventing the breakdown of cGMP, sildenafil leads to increased levels of this molecule, promoting relaxation and dilation of vascular smooth muscle. This ultimately results in lowered pulmonary arterial pressure.

In terms of pharmacokinetics, sildenafil is rapidly absorbed, with effects noticeable within 30-60 minutes of administration. The peak plasma concentration occurs in approximately 1 hour. It has an elimination half-life of about four hours, meaning it's cleared from the body relatively quickly. This action is particularly beneficial in managing PAH, which can significantly improve the quality of life for those affected.

Dosage & Administration

Standard regimens

For treating PAH, the standard regimen of Assurans involves administering 20 mg three times daily. This can be taken with or without food, but consistency in timing is essential. Adhering strictly to this dosage is crucial, as adjustments are made based on individual response and side effects. An experienced healthcare provider tailors these regimens, ensuring optimal results.

Adjustments by patient type

Specific populations may require careful consideration regarding their dosage. For the elderly, while there's no need for an initial adjustment, starting with the lowest effective dose is advised to monitor for adverse effects.

In patients suffering from chronic conditions like renal or hepatic impairment, caution is vital. Those with severe hepatic dysfunction should avoid sildenafil altogether, while individuals with renal impairment may need to limit their dosage or be closely monitored. This tailored approach maximises safety and effectiveness.

Contraindications & Side Effects

Common

Several side effects commonly accompany sildenafil usage. These include headaches, flushing, nasal congestion, and mild visual disturbances. Approximately 10-15% of patients may experience some of these mild effects.

Most side effects can be managed with simple adjustments like taking the medication at different times or with food. Regular communication with healthcare providers ensures that these effects are monitored and addressed promptly.

Rare but serious

While most side effects are mild, there are serious risks associated with sildenafil use, particularly in specific populations. Rarely, patients may experience severe hypotension, priapism, or sudden vision loss. According to Australian safety data, these severe events are uncommon but need immediate attention.

Monitoring patients, especially those on other medications, is vital to avoid potential complications. This also highlights the importance of comprehensive patient education regarding possible risks and symptoms to watch for.

Comparable Medicines

Alternatives table

Pros and cons list

When comparing Assurans to other medications, several points stand out:

• Advantages: Assurans is often considered cost-effective, especially for treating PAH.
• Disadvantages: Potential for common side effects can lead to discontinuation; monitoring for serious effects is essential.

Considering these factors helps in determining the most suitable treatment option tailored to individual needs.

Current Research & Trends

Research on sildenafil, notably through the lens of Assurans, is generating significant interest both in Australia and globally. Studies from 2022 onwards have explored new therapeutic applications beyond erectile dysfunction and pulmonary arterial hypertension (PAH). There’s particular attention on its cardiovascular effects and potential role in treating altitude sickness. Internationally, trials have examined the efficacy of lower dosages, like Assurans 20 mg, to maintain safety while enhancing patient comfort.

In Australia, research teams are also analysing sildenafil's impacts on endothelial function. This could lead to expanded uses for Assurans, as enhanced vascular health may play a critical role in managing chronic conditions. These findings have implications for how healthcare professionals prescriptively apply Assurans, ensuring they can offer tailored advice to patients about both use and dosage.

Common Patient Questions

Consultations at Australian pharmacies often reveal common concerns about Assurans. Patients frequently ask about how Assurans works and its side effects. Understanding the uses of Assurans 20 mg can help clarify its role in managing PAH and related conditions.

Many are also curious about whether they can purchase Assurans without a prescription. It’s vital for patients to know that while it may be possible in some cases, safety regulations typically require a prescription to ensure proper use. Common questions often include:

• What is the best way to take Assurans?
• Are there any interactions with other medications?
• What should I do if I miss a dose?

Providing clear answers can alleviate patient anxieties and promote safe practices.

Regulatory Status

TGA approval

The Therapeutic Goods Administration (TGA) oversees the approval of Assurans in Australia. It initially received approval for specific indications, including PAH, and remains a prescription-only medication due to safety standards aimed at preventing misuse.

This regulatory framework plays a vital role in maintaining patient safety, ensuring that only qualified professionals prescribe Assurans based on individual health needs.

PBS subsidy details

Assurans is included in the Pharmaceutical Benefits Scheme (PBS), which significantly helps reduce patient costs. To qualify for the subsidy, specific criteria must be met, including medical necessity and ongoing patient assessment.

The inclusion of Assurans in the PBS improves accessibility, allowing more individuals to afford treatment. This has profound implications for overall health outcomes in the community.

Visual Recommendations

Infographics: PBS pricing, pharmacy networks

Effective education tools like infographics can greatly enhance understanding of the PBS pricing structure and how pharmacy networks operate in Australia. Creating visual aids can help patients navigate where to purchase Assurans, illustrating key pricing strategies and availability in different networks.

These resources can aid pharmacists in communicating with patients, ensuring clarity in both access and understanding of Assurans 20 mg

Buying & Storage Advice

In-store vs online purchase tips in Australia

When procuring Assurans, whether through physical pharmacies or online, safety is paramount. For in-store purchases, patients should seek reputable pharmacies, and inquire about the availability of Assurans 20 mg tablets.

Online purchasers should verify authenticity through legitimate suppliers and ensure prescription requirements are met before buying Assurans online. Reliable sources will typically display their licensing and customer reviews to help build trust.

Storage in Australian household conditions

To maintain effectiveness, storing Assurans properly is crucial. Suitable conditions are:

• Keep below 30°C (86°F).
• Avoid exposure to humid conditions.
• Store in original packaging, away from light.

Adhering to these guidelines helps preserve the integrity of Assurans, ensuring it remains effective for patients.

Guidelines for Proper Use

Pharmacist guidance in Australia

Pharmacists play an essential role in guiding patients on the appropriate use of Assurans. Upon consultation, patients should discuss:

• Medical history and existing conditions.
• Potential side effects to monitor.
• Adherence to dosing schedules.

Such discussions ensure safe and effective usage, allowing for personalised treatment plans.

Patient safety recommendations

For patients using Assurans, following safety recommendations is critical. These include:

• Adhering to prescribed dosages.
• Monitoring for any adverse side effects.
• Communicating changes in health status with healthcare providers.

By doing so, patients can optimise the benefits of Assurans while minimizing risks.